Long-term results of gastric bypass surgery in morbidly obese type 1 diabetes patients.

BACKGROUND Long-term effects of bariatric surgery in morbidly obese type 1 patients are unknown. Five to eight-year experience in the case series of type 1 diabetes subjects is presented. METHODS Three poorly controlled type 1 diabetes patients, aged 19, 23, and 28 underwent Roux-en-Y gastric bypass surgery. RESULTS Their maximum body weight reduction noted during the follow-up was between 27% and 31% of baseline body weight, insulin requirement decreased from 0.6-0.95 to 0.3-0.83 IU/kg, and absolute reduction in HbA(1c) was 3-4%. Significant improvement in blood pressure, plasma lipid profile, and microalbuminuria was noted. CONCLUSIONS RYGB surgery in morbidly obese type 1 diabetes patients leads to a significant and maintained weight loss and results in remarkable improvement in blood glucose control and concomitant disorders. Bariatric surgery should be recommended to significantly obese type 1 diabetes patients as a means of reduction of vascular complications risk.